Proprietary mix of 8 anticancer natural ingredients with innovative NANO-LIPOSOMAL direct delivery
Phytochemical extracted from Black Cumin. Thymoquinone has evidently proved its activity as hepatoprotective, anti-inflammatory, antioxidant, cytotoxic and anti-cancer chemical, with specific mechanisms of action.
Thymoquinone exhibits anticancer activity via numerous mechanisms of action, specifically by showing selective antioxidant and oxidant activity, interfering with DNA structure, affecting carcinogenic signaling molecules/pathways. Thymoquinone has antioxidant, immunomodulatory activities, interferes with DNA structure and synthesis, targets carcinogenic signaling pathways, suppresses cancer cell migration and invasion. Explore scientific papers on Thymoquinone and cancers here
Artemisinin, also called qinghaosu, mostly used as antimalarial medicine is derived from the sweet wormwood plant, Artemisia annua (Wormwood). Artemisinin is distilled from the dried leaves or its flower clusters.
Artemisinin kills cancer cells, yeasts, parasites and viruses by acting in various ways, especially on mitochondrial mechanisms and can also boost the immune system. One way it acts on cancer cells is by reacting with intracellular iron free radicals which then kills the cell it contains. Cancer cells require and uptake a large amount of iron to proliferate and that makes them more susceptible to the cytotoxic effect of artemisinin than normal cells. Explore scientific researches on Artemisinin and cancers here
Extracted from tripterygium wilfordii plant, triptolide contains three epoxy groups of diterpene lactone compounds, and it has anti-tumor, anti-inflammatory and immunosuppressive activities.
Triptolide exerts proapoptotic and anti-proliferative effects. Induces apoptosis by regulating apoptosis-related protein expression and and reduces tumor size or restricts tumor growth. It induces cell apoptosis through the NF-κB pathway, involved in the process of inflammation, stress, cell growth and proliferation. Furthermore, it sensitizes tumor cells to other therapeutic methods, such as chemoradiation. Explore scientific researches on Triptolide and cancers here
Obtained from Cucurbita Andreana, ancient wild squash from South America. It is egg sized, not palatable, and it contains abundance of full spectrum cucurbitacins. Considered as a fertile ground for novel antitumor drugs.
A class of biochemical compounds (triterpenes) that possess immense pharmacological potential that and have unique anticancer properties. They suppress the growth of the tumor by blocking STAT3 growth activator. STAT3 mediates the expression of a variety of genes in response to cell stimuli and plays a key role in cell growth and apoptosis. Explore scientific researches on Cucurbitacins and cancers here
Obtained from the root bark of Tripterygium Wilfordii, Celastrol exhibits antioxidant, anti-inflammatory, anticancer, and insecticidal activities.
Celastrol suppresses Akt activation and inhibits the expression of anti-apoptotic proteins. Celastrol induces apoptosis in cancer cells, supported by DNA fragmentation, caspase-3 activation and PARP (family of proteins involved in cellular processes such as DNA repair and apoptosis). Further to that Celastrol suppresses proliferation of drug-resistant cancer cell lines and synergistically enhances the effects of chemoradiation. Explore scientific researches on Celastrol and cancers here
Extracted from the rind of the fruit of Garcinia indica, a plant found in tropical regions. Its antioxidative, chelating, free radical scavenging and anti-glycation activity are well studied.
Garcinol has been reported to display strong cancer growth inhibitory activity through induction of caspase-3 activation. This activation plays a central role in the execution-phase of cell apoptosis induction, which is a pivotal mechanism for its anticancer action. Garcinol has anticancer activity via inhibition of STAT-1 growth factor activation. It has also antioxidant activity, as well as it is strong anti-inflammatory agent. Explore scientific researches on Garcinol and cancers here
Isolated from various parts of the Mangosteen friut, its pharmacological properties have been recognized in numerous studies. It shows strong effects by targeting a number of vital cellular factors through various mechanisms of action.
Named also alpha-mangostin, has been reported to interfere with all the major stages of carcinogenesis: initiation, promotion, and progression. Main feature of mangostin is its antiproliferative effect attributable to cell-cycle arrest by affecting the cyclins cdc2 and p27 expression, proteins that are key players in cell cycle regulation. Mangostin has several other antimetastatic mechanisms that you can find in the researches. Explore scientific researches on Mangostin and cancers here
Extracted from the root of Withania Somnifera (Ashwagandha), revered herb of the Indian Ayurvedic system of medicine as a tonic named Rasayana. It is used for various kinds of diseases, specially as a nervine tonic.
Withaferin A has been scientifically validated for different pharmacological activities: anti–cancer, adaptogenic, anti–stress, anti–convulsant, immunomodulatory, neurological, anti–inflammatory, anti–tumor, cardioprotective, and neuroprotective activities. Scientific data shows that Withaferin-A suppresses carcinogenesis by its potent antioxidative, antiinflammatory, antiproliferative and apoptosis-inducing properties. Moreover, it sensitizes resistant cancer cells to chemotherapeutic agents. Explore scientific researches on Withaferin-A and cancers here
NANO-LIPOSOMAL DELIVERY SYSTEM
what is nano-liposomal delivery and why it matters
Administered intravenously, medication’s bioavailability (the fraction of an administered dose of unchanged drug that reaches the cells) is 100%. However, administered orally, it decreases to 5%, even as low as 1%.
There are several factors that play a role in limiting the bioavailability: solubility of the compound, gastric and colon pH, metabolism by gut microflora, absorption across the intestinal wall, active efflux mechanism in the intestine, the liver first-pass metabolism effect and elimination from circulation.
ReVittA ingredients are structured down to nano particles surrounded with 26 nm sized lipospheres that protects them from negative bioavailability factors, making them available for direct absorption to the cells.
The extended circulation lifetime of ReVittA is achieved by the use of liposomes, delivering their curative payload directly to cells, thus makingReVittAvery efficient.