In latest developments it has emerged that Chloroquine, a synthetic and cheaper to produce analogue of naturally bound Quinine, could be used against CoViD-19 as there are anecdotal cases where it helped in off-label usage, to patients in conjunction with an antibiotic named Azithromycin.
Chloroquine has been used for treatment of Malaria and can have some unwanted side effects; from gastrointestinal disturbances, headaches, skin reactions, hypotension, convulsions, extrapyramidal symptoms and visual disturbances to ssychiatric side effect such as confusion, disorientation, ideas of persecution, agitation, outbursts of violence, loss of interest, feeling sad, up to suicidal ideas. Futhermore, Chloroquine treatment resistance is growing more and more.
On the other hand there is an alternative to Chloroquine – Artemisinin, that has virtually no side effects, have better results against malaria, and no resistance have been noticed. If we take that in account could we say that Artemisinin is a better option for CoViD-19 treatment? It is hard to say, as there are no reports if it has been used in these cases. Can we just assume so? Sure we can. But not to be taken for granted.
Worth noting is that Artemisinin is one of the ingredients in ReVitt A
Here are the research papers that compare Artemisinin versus Chloroquine in cases of Malaria:
From chloroquine to artemisinin-based combination therapy: the Sudanese experience.
Is Chloroquine Better than Artemisinin Combination Therapy as First Line Treatment in Adult Nigerians with Uncomplicated Malaria?-A Cost Effectiveness Analysis
No Plasmodium falciparum Chloroquine Resistance Transporter and Artemisinin Resistance Mutations, Haiti
Artemisinin-based combination therapy (ACT) for treating non-severe malaria due to Plasmodium vivax
Are We Headed for a New Era of Malaria Drug Resistance?
In Mozambique, chloroquine susceptibility returns and artemisinin resistance is not yet detected
Chinese herb reveals vital malaria weakness
In vitro susceptibility of Tanzanian wild isolates of Plasmodium falciparum to artemisinin, chloroquine, sulfadoxine/pyrimethamine and mefloquine
ARTEMISININ, The new antimalarial drug from China
Comparative Study on the Effects of Chloroquine and Artesunate on Histopathological Damages Caused by Plasmodium berghei in Four Vital Organs of Infected Albino Mice
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