In light of the new findings that 40% of the Covid-19 deaths are related to cardiovascular complications and those problems are related to endothelial issues and blood clotting, we would like to present you with several scientific studies that ReVitt-A containing Thumoquinone, could potentially address those issues.

Namely, these in-vivo studies show that Thymoquinone has Anticoagulant, endothelial improving, lung injury attenuative, repairing, protective and anti-inflamatory properties

The studies are as follows:

A new agent for treatment of acute respiratory distress syndrome: thymoquinone
„Conclusions: This study revealed that thymoquinone improved oxygenation while both thymoquinone and steroids protect lung tissue from hazardous effects of human gastric juice (pH 1.2) histopathologically.“
Thymoquinone improves aging-related endothelial dysfunction in the rat mesenteric artery
“TQ improves endothelial function in aging, at least in part, through inhibition of oxidative stress and normalization of the angiotensin system „
Attenuation of oxidative stress-induced vascular endothelial dysfunction by thymoquinone
„These results suggest that TQ can protect against pyrogallol-induced endothelial dysfunction which probably results from its potent antioxidant capacity that leads to an increase in NO production as well as its ability to enhance the generation and bioavailability of NO.“
Intestinal, Airway, and Cardiovascular Relaxant Activities of Thymoquinone
“ These data suggest smooth and cardiac muscle relaxant activity of TQ possibly mediated”
The endothelium-dependent, soluble guanylyl cyclase-dependent augmentation caused by thymoquinone in isolated porcine coronary arteries is mediated by cIMP (1146.6)
“Results: Thymoquinone caused a sustained further increase of tension in rings with endothelium”
Comparative evaluation of anti-inflammatory properties of thymoquinone and curcumin
“These results suggest that TQ is more potent in inhibiting the inflammatory changes associating asthma.”
Thymoquinone inhibits inflammation, neoangiogenesis and vascular remodeling
“Our study demonstrates that TQ attenuated the inflammatory reaction by antagonizing IL-4/− 5 while the anti-neoangiogenesis effect of TQ is mediated by inhibition of vascular endothelial growth factor (VEGF)”
Protective effect of thymoquinone improves cardiovascular function, and attenuates oxidative stress, inflammation and apoptosis by mediating the PI3K/Akt pathway
“ the present study demonstrated that the protective effect of thymoquinone improves the cardiovascular function through antioxidative, anti-inflammatory and anti-apoptotic effects”
Pathological Study on the Role of Thymoquinone in Experimentally Induced Acute Lung Injury
“It could be concluded that TQ restores lung architecture and reduces inflammatory Immunomodulators in ALI.”
Thymoquinone modulates nitric oxide production and improves organ dysfunction of sepsis
“These findings suggest that thymoquinone prevents sequels of the multiple organ failure syndrome of sepsis by modulating the production of NO and its inflammatory sequela, and adjusting vascular responsiveness.”
Thymoquinone Modulates Blood Coagulation in Vitro via Its Effects on Inflammatory and Coagulation Pathways
“This provides a proof-of-concept and points to pursuit of in vivo mechanistic, pharmacokinetic and pharmacodynmaic investigations to evaluate the potential use of the natural supplement THQ as an alternative to preventative anticoagulants and/or for use as a supplement to existing therapies for infections, chemotherapies, and anticoagulant therapies.”
In vitro study for antiplatelet activity of ‘Kalonji’ (Nigella sativa) extracts using aspirin as standard
“Nigella sativa showed remarkable antiplatelet activity in case of maximum used concentration”
Thymoquinone effectively alleviates lung fibrosis induced by paraquat herbicide through down-regulation of pro-fibrotic genes and inhibition of oxidative stress
“This study indicated that TQ has the preventive and therapeutic potentials for the treatment of lung fibrosis by inhibition of oxidative stress and down-regulation of profibrotic genes.”
Thymoquinone attenuates lung injury induced by chronic toluene exposure
Thymoquinone blocks lung injury and fibrosis by attenuating bleomycin-induced oxidative stress
Thymoquinone attenuates cyclophosphamide-induced pulmonary injury
“Our results suggest that TQ produces a protective mechanism against CP-induced pulmonary damage and suggest a role of oxidative stress and inflammation in the pathogenesis.”
Comparative evaluation of thymoquinone and methotrexate in lung inflammation in murine model of rheumatiod arthritis
“Thus thymoquinone can be a potential therapy for rheumatoid lung and needs further evaluation in human models.”
Thymoquinone attenuates monocrotaline-induced pulmonary artery hypertension via inhibiting pulmonary arterial remodeling
“TQ ameliorates MCT-induced pulmonary artery hypertension by inhibiting pulmonary arterial remodeling partially via p38MAPK/NF-κB signaling pathway”