RESEARCHES:

• Use of artemisinin and its derivatives to treat HPV-infected/transformed cells and cervical cancer: a review
  Artemisinin / Uterus-Cervix / (In Vitro, In Vivo, Clinical Basic)
• p8 attenuates the apoptosis induced by dihydroartemisinin in cancer cells through promoting autophagy
  Artemisinin / Colon, Uterus-Cervix / (In Vitro, In Vivo, Chemo, Synergy)
• Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines
  Artemisinin / Neuro / (In Vitro)
• Additive Cytotoxic Effects of Dihydroartemisinin and Sodium Salicylate on Cancer Cells
  Artemisinin / Leukaemia / (In Vitro)
• Artemisinin-derived dimer ART-838 potently inhibited human acute leukemias, persisted in vivo, and synergized with antileukemic drugs
  Artemisinin / Leukaemia / (In Vitro, In Vivo, Chemo, Synergy)
• Artesunate in the treatment of metastatic uveal melanoma – First experiences
  Artemisinin / Melanoma / (Clinical Basic, Chemo, Synergy)
• Mn (II) mediated degradation of artemisinin based on Fe3O4@MnSiO3-FA nanospheres for cancer therapy in vivo
  Artemisinin / Lung / (In Vivo)
• Artesunate combined with vinorelbine plus cisplatin in treatment of advanced non-small cell lung cancer: A randomized controlled trial
  Artemisinin / Lung / (Clinical Basic, Chemo)
• Artemisinin induces A549 cell apoptosis dominantly via a reactive oxygen species-mediated amplification activation loop among caspase-9, -8 and -3
  Artemisinin / Lung / (In Vitro)
• Inhibition of autophagy by chloroquine potentiates synergistically anti-cancer property of artemisinin by promoting ROS dependent apoptosis
  Artemisinin / Lung / (In Vitro)
• Dihydroarteminsin-Induced Apoptosis is not Dependent on the Translocation of Bim to the Endoplasmic Reticulum in Human Lung Adenocarcinoma Cells
  Artemisinin / Lung / (In Vitro)
• Artesunate induces apoptosis via a Bak-mediated caspase-independent intrinsic pathway in human lung adenocarcinoma cells
  Artemisinin / Lung / (In Vitro)
• DHA regulates angiogenesis and improves the efficiency of CDDP for the treatment of lung carcinoma
  Artemisinin / Lung / (In Vitro, In Vivo, Chemo, Synergy)
• Enhanced apoptotic effects of dihydroartemisinin-aggregated gelatin and hyaluronan nanoparticles on human lung cancer cells
  Artemisinin / Lung / (In Vitro)
• A survey on anticancer effects of artemisinin, iron, miconazole, and butyric acid on 5637 (bladder cancer) and 4T1 (Breast cancer) cell lines
  Artemisinin / Breast, Bladder / (In Vitro)
• Artesunate Induces Apoptosis of Bladder Cancer Cells by miR-16 Regulation of COX-2 Expression
  Artemisinin / Bladder / (In Vitro, In Vivo)
• Synergic effects of artemisinin and resveratrol in cancer cells
  Artemisinin, Resveratrol / Liver, Uterus-Cervix / (In Vitro, Synergy)
• Artemisinin Represses Telomerase Subunits and Induces Apoptosis in HPV-39 Infected Human Cervical Cancer Cells
  Artemisinin / Uterus-Cervix / (In Vitro)
• Enhancement of cytotoxicity of artemisinin toward cancer cells by transferrin-mediated carbon nanotubes nanoparticles
  Artemisinin / Breast / (In Vitro, In Vivo)
• Dihydroartemisinin induces apoptosis of cervical cancer cells via upregulation of RKIP and downregulation of bcl-2
  Artemisinin / Uterus-Cervix / (In Vitro, In Vivo)
• Cytotoxic Effect of Artemisinin and Its Derivatives on Human Osteosarcoma Cell Lines
  Artemisinin / Bone-Cartilage / (In Vitro)
• Influence of Artemisia annua extract derivatives on Proliferation, apoptosis and metastasis of osteosarcoma cells
  Artemisinin / Bone-Cartilage / (In Vitro)
• Artemisinin and Curcumin inhibit Drosophila brain tumor, prolong life span, and restore locomotor activity
  Artemisinin, Curcumin / Brain / (In Vivo)
• Artemisinin reduces cell proliferation and induces apoptosis in neuroblastoma
  Artemisinin / Neuro / (In Vitro, In Vivo)
• On the preparation of transferrin modified artesunate nanoliposomes and their glioma-targeting treatment in-vitro and in-vivo
  Artemisinin / Brain / (In Vitro, In Vivo)
• Artemisinin inhibits neuroblastoma proliferation through activation of AHP-activated protein kinase (AMPK) signaling
  Artemisinin / Neuro / (In Vitro)
• Dihydroartemisinin exhibits anti-glioma stem cell activity through inhibiting p-AKT and activating caspase-3
  Artemisinin / Brain, Stem_Cell / (In Vitro)
• Artesunate Enhances the Antiproliferative Effect of Temozolomide on U87MG and A172 Glioblastoma Cell Lines
  Artemisinin / Brain / (In Vitro, Chemo, Synergy)
• Dihydroartemisinin inhibits the mammalian target of rapamycin-mediated signaling pathways in tumor cells
  Artemisinin / Prostate, Lymphoma, Leukaemia, Myeloma, Uterus-Cervix, Brain, Bone-Cartilage / (In Vitro)
• Growth inhibitory effect of dihydroartemisinin on Bcr/Abl+ chronic myeloid leukemia K562 cells involve AKT, ERK and NF-κB modulation
  Artemisinin / Leukaemia / (In Vitro)
• Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells
  Artemisinin / Lung, Breast, Prostate, Melanoma, Leukaemia, Kidney, Ovarian, Neuro / (In Vitro)
• Dihydroartemisinin induces autophagy and inhibits the growth of iron-loaded human myeloid leukemia K562 cells via ROS toxicity
  Artemisinin / Leukaemia / (In Vitro)
• Artesunate overcomes drug resistance in multiple myeloma by inducing mitochondrial stress and non-caspase apoptosis
  Artemisinin / Myeloma / (In Vitro)
• Artesunate induces apoptosis and inhibits growth of Eca109 and Ec9706 human esophageal cancer cell lines in vitro and in vivo
  Artemisinin / Gastric / (In Vitro, In Vivo)
• Dihydroartemisinin Accentuates the Anti-Tumor Effects of Photodynamic Therapy via Inactivation of NF-κB in Eca109 and Ec9706 Esophageal Cancer Cells
  Artemisinin / Gastric / (In Vitro)
• In vitro anti-cancer effects of artemisone nano-vesicular formulations on melanoma cells
  Artemisinin / Melanoma / (In Vitro)
• Differential Effect of Artemisinin Against Cancer Cell Lines
  Artemisinin / Myeloma / (In Vivo)
• Enhanced delivery of artemisinin and its analogues to cancer cells by their adducts with human serum transferrin
  Artemisinin / Liver / (In Vitro)
• Experimental Therapy of Hepatoma with Artemisinin and Its Derivatives: In vitro and In vivo Activity, Chemosensitization, and Mechanisms of Action
  Artemisinin / Liver / (In Vitro, In Vivo)
• Dihydroartemisinin exhibits antitumor activity toward hepatocellular carcinoma in vitro and in vivo
  Artemisinin / Liver / (In Vitro, In Vivo)
• Dihydroartemisinin induces endoplasmic reticulum stress-mediated apoptosis in HepG2 human hepatoma cells
  Artemisinin / Liver / (In Vitro)
• Artemisinin inhibits in vitro and in vivo invasion and metastasis of human hepatocellular carcinoma cells
  Artemisinin / Liver / (In Vitro, In Vivo)
• Dihydroartemisinin induces apoptosis in colorectal cancer cells through the mitochondria-dependent pathway
  Artemisinin / Colon / (In Vitro)
• A Randomised, Double Blind, Placebo-Controlled Pilot Study of Oral Artesunate Therapy for Colorectal Cancer
  Artemisinin / Colon / (Clinical Full)
• Dihydroartemisinin Enhances Apo2L/TRAIL-Mediated Apoptosis in Pancreatic Cancer Cells via ROS-Mediated Up-Regulation of Death Receptor 5
  Artemisinin / Pancreatic / (In Vitro)
• The activation of c-Jun NH2-terminal kinase is required for dihydroartemisinin-induced autophagy in pancreatic cancer cells
  Artemisinin / Pancreatic / (In Vitro)
• Anticancer Effect of Dihydroartemisinin (DHA) in a Pancreatic Tumor Model Evaluated by Conventional Methods and Optical Imaging
  Artemisinin / Pancreatic / (In Vitro, In Vivo)
• Artemisinin triggers a G1 cell cycle arrest of human Ishikawa endometrial cancer cells and inhibits Cyclin Dependent Kinase-4 promoter activity and expression by disrupting NF-kB transcriptional signaling
  Artemisinin / Uterus-Cervix / (In Vitro)
• Artemisinin inhibits gastric cancer cell proliferation through upregulation of p53
  Artemisinin / Gastric / (In Vitro)
• Anti-cancer activity of DHA on gastric cancer—an in vitro and in vivo study
  Artemisinin / Gastric / (In Vitro, In Vivo)
• Artesunate inhibits the growth of gastric cancer cells through the mechanism of promoting oncosis both in vitro and in vivo
  Artemisinin / Gastric / (In Vitro, In Vivo)
• Artesunate inhibits the growth and induces apoptosis of human gastric cancer cells by downregulating COX-2
  Artemisinin / Gastric / (In Vitro)
• Apoptosis of nasopharyngeal carcinoma cells line CNE-2 induced by dihydroartemisinin and its possible mechanism
  Artemisinin / Head_&_Neck / (In Vitro)
• Bioinformatic and experimental fishing for artemisinin-interacting proteins from human nasopharyngeal cancer cells
  Artemisinin / Head_&_Neck / (In Vitro)
• Activity of Novel Plant Extracts Against Medullary Thyroid Carcinoma Cells
  Artemisinin / Thyroidal / (In Vitro)
• Modeling and prediction of cytotoxicity of artemisinin for treatment of the breast cancer by using artificial neural networks
  Artemisinin / Breast / (In Vitro)
• pH-Responsive Artemisinin Derivatives and Lipid Nanoparticle Formulations Inhibit Growth of Breast Cancer Cells In Vitro and Induce Down-Regulation of HER Family Members
  Artemisinin / Breast / (In Vivo)
• Selective toxicity of dihydroartemisinin and holotransferrin toward human breast cancer cells
  Artemisinin / Breast / (In Vitro)
• Artemisinin-Transferrin Conjugate Retards Growth of Breast Tumors in the Rat
  Artemisinin / Breast / (In Vivo)
• Effects of Artemisinin Dimers on Rat Breast Cancer Cells In Vitro and In Vivo
  Artemisinin / Breast / (In Vitro, In Vivo)
• Experimental treatment of breast cancer-bearing BALB/c mice by artemisinin and transferrin-loaded magnetic nanoliposomes
  Artemisinin / Breast / (In Vivo)
• Dihydroartemisinin Exerts Its Anticancer Activity through Depleting Cellular Iron via Transferrin Receptor-1
  Artemisinin / Breast / (In Vitro)
• In vitro and in vivo studies of artemisin endoperoxides
  Artemisinin / Lung, Breast, Prostate, Melanoma, Leukaemia, Pancreatic, Brain / (In Vitro, In Vivo)
• Artesunate exerts specific cytotoxicity in retinoblastoma cells via CD71
  Artemisinin / Eye_Cavity / (In Vitro)
• Artesunate inhibits growth and induces apoptosis in human osteosarcoma HOS cell line in vitro and in vivo
  Artemisinin / Bone-Cartilage / (In Vitro, In Vivo)
• Artesunate induces ROS- and p38 MAPK-mediated apoptosis and counteracts tumor growth in vivo in embryonal rhabdomyosarcoma cells
  Artemisinin / Bone-Cartilage / (In Vivo)
• Artemisinin Blocks Prostate Cancer Growth and Cell Cycle Progression by Disrupting Sp1 Interactions with the Cyclin-dependent Kinase-4 (CDK4) Promoter and Inhibiting CDK4 Gene Expression
  Artemisinin / Prostate / (In Vitro)
• Dihydroartiminisin inhibits the growth and metastasis of epithelial ovarian cancer
  Artemisinin / Ovarian / (In Vitro, In Vivo)
• The Antimalaria Agent Artemisinin Exerts Antiangiogenic Effects in Mouse Embryonic Stem Cell-Derived Embryoid Bodies
  Artemisinin / Stem_Cell / (In Vitro)
• Artemisinin reduces human melanoma cell migration by down-regulating αVβ3 integrin and reducing metalloproteinase 2 production
  Artemisinin / Melanoma / (In Vitro)
• In vitro anti-cancer effects of artemisone nano-vesicular formulations on melanoma cells
  Artemisinin / Melanoma / (In Vitro)
• The redox antimalarial dihydroartemisinin targets human metastatic melanoma cells but not primary melanocytes with induction of NOXA-dependent apoptosis
  Artemisinin / Melanoma / (In Vitro)
• Effect of artesunate on immune cells in ret-transgenic mouse melanoma model
  Artemisinin / Melanoma / (In Vivo)
• Calcium and survivin are involved in the induction of apoptosis by dihydroartemisinin in human lung cancer SPC-A-1 cells
  Artemisinin / Lung / (In Vitro)
• First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases
  Artemisinin / Lung / (In Vivo)
• Dihydroartemisinin induces apoptosis in skin cancer cell line A-431 via ROS pathway
  Artemisinin / Skin / (In Vitro)
• Dihydroartemisinin suppresses growth of squamous cell carcinoma A431 cells by targeting the Wnt/β-catenin pathway
  Artemisinin / Skin / (In Vitro)
• Inhibition of angiogenesis in vivo and growth of Kaposi\’s sarcoma xenograft tumors by the anti-malarial artesunate
  Artemisinin / Skin / (In Vivo)
• Artemisinin Represses Telomerase Subunits and Induces Apoptosis in HPV-39 Infected Human Cervical Cancer Cells
  Artemisinin / Uterus-Cervix / (In Vitro)
• Artemisinin derivative artesunate induces radiosensitivity in cervical cancer cells in vitro and in vivo
  Artemisinin / Uterus-Cervix / (In Vitro, In Vivo)
• Interferon-α enhances artemisinin-induced differentiation of HL-60 leukemia cells via a PKCα/ERK pathway
  Artemisinin / Leukaemia / (In Vitro)
• Artemisinin Induces Apoptosis in Human Cancer Cells
  Artemisinin / Leukaemia / (In Vitro)
• Synergic effects of artemisinin and resveratrol in cancer cells
  Artemisinin, Resveratrol / Liver, Uterus-Cervix / (In Vitro, Synergy)
• Artemisinin inhibits gallbladder cancer cell lines through triggering cell cycle arrest and apoptosis
  Artemisinin / Gallbladder / (In Vitro, In Vivo)
• Artemisinin: an alternative treatment for oral cancer
  Artemisinin / Oral / (In Vitro)
• Effects of artemisinin and its derivatives on growth inhibition and apoptosis of oral cancer cells
  Artemisinin / Oral / (In Vitro)
• Artemisinin: An Alternative Treatment for Oral Squamous Cell Carcinoma
  Artemisinin / Oral / (In Vitro)
• Artemisinin Inhibits Tumor Lymphangiogenesis by Suppression of Vascular Endothelial Growth Factor C
  Artemisinin / Lymphoma / (In Vitro)
• LyP-1 Modification To Enhance Delivery of Artemisinin or Fluorescent Probe Loaded Polymeric Micelles to Highly Metastatic Tumor and Its Lymphatics
  Artemisinin / Lymphoma / (In Vitro, In Vivo)
• Repurposing the anti-malarial drug artesunate as a novel therapeutic agent for metastatic renal cell carcinoma due to its attenuation of tumor growth, metastasis, and angiogenesis
  Artemisinin / Kidney / (In Vitro, In Vivo)
• Dihydroartemisinin (DHA) induces ferroptosis and causes cell cycle arrest in head and neck carcinoma cells
  Artemisinin / Head_&_Neck / (In Vitro)
• Dihydroartemisinin inhibits cell proliferation by induced G1 arrest and apoptosis in human nasopharyngealcarcinoma cells
  Artemisinin / Head_&_Neck / (In Vitro)
• Down-regulation of BMI-1 cooperates with artemisinin on growth inhibition of nasopharyngeal carcinoma cells
  Artemisinin / Head_&_Neck / (In Vitro)
• Artesunate inhibits the growth of gastric cancer cells through the mechanism of promoting oncosis both in vitro and in vivo
  Artemisinin / Gastric / (In Vitro, In Vivo)
• Inhibition of human cancer cell line growth and human umbilical vein endothelial cell angiogenesis by artemisinin derivatives in vitro
  Artemisinin / Stem_Cell / (In Vitro)
• Synergistic Inhibition of Angiogenesis by Artesunate and Captopril In Vitro and In Vivo
  Artemisinin / Stem_Cell / (In Vitro, In Vivo, Chemo, Synergy)
• In vivo study of effects of artesunate nanoliposomes on human hepatocellular carcinoma xenografts in nude mice
  Artemisinin / Liver / (In Vivo)
• Preparation of isoliquiritigenin-loaded nanostructured lipid carrier and the in vivo evaluation in tumor-bearing mice
  Artemisinin / Liver / (In Vivo)
• Artemisinin selectively decreases functional levels of estrogen receptor-alpha and ablates estrogen-induced proliferation in human breast cancer cells
  Artemisinin / Breast / (In Vitro)
• Artemisinin triggers a G1 cell cycle arrest of human Ishikawa endometrial cancer cells and inhibits cyclin-dependent kinase-4 promoter activity and expression by disrupting nuclear factor-κB transcriptional signalin
  Artemisinin / Uterus-Cervix / (In Vitro)
• A preliminary study on combination therapy of artemisinin dimer oxime and topotecan against nonsmall cell lung cancer in mice
  Artemisinin / Lung / (In Vivo, Chemo, Synergy)
• Synthesis of Artemisinin–Estrogen Hybrids Highly Active against HCMV, P. falciparum, and Cervical and Breast Cancer
  Artemisinin / Breast, Uterus-Cervix / (In Vitro)
• The selectivity of artemisinin-based drugs on human lung normal and cancer cells
  Artemisinin / Lung / (In Vitro)
• Dried leaf artemisia annua efficacy against non-small cell lung cancer
  Artemisinin / Lung / (In Vitro, In Vivo)
• Arsenic trioxide and artemisinin act synergistically to kill tumor cells in vitro.
  Artemisinin / Lung, Liver, Uterus-Cervix / (In Vitro, Chemo, Synergy)
• Artesunate enhances radiosensitivity of esophageal cancer cells by inhibiting the repair of DNA damage
  Artemisinin / Gastric / (In Vitro, Chemo, Synergy)
• Effect of artemisinin on proliferation and apoptosis-related protein expression in vivo and in vitro
  Artemisinin / Brain / (In Vitro, In Vivo)
• Dihydroartemisinin induces apoptosis and inhibits proliferation, migration, and invasion in epithelial ovarian cancer via inhibition of the hedgehog signaling pathway
  Artemisinin / Ovarian / (In Vitro)
• Thermal degradation, kinetic analysis and evaluation of biological activity on human melanoma for artemisinin
  Artemisinin / Melanoma / (In Vitro)
• Dihydroartemisinin potentiates antitumor activity of 5-fluorouracil against a resistant colorectal cancer cell line
  Artemisinin / Colon / (In Vitro, Chemo, Synergy)
• Dihydroartemisinin increases apoptosis of colon cancer cells through targeting Janus kinase 2/signal transducer and activator of transcription 3 signaling
  Artemisinin / Colon / (In Vitro)
• Malaria and Burkitt\’s lymphoma an in silico analysis of gene expression links between malaria and burkitt\’s lymphoma and potential anticancer activity of Artemisinin derivatives
  Artemisinin / Lymphoma / (In Vitro)
• Antimalarial Dihydroartemisinin triggers autophagy within HeLa cells of human cervical cancer through Bcl-2 phosphorylation at Ser70
  Artemisinin / Ovarian / (In Vitro)
• In vitro assessment of cytotoxic, genotoxic and mutagenic effects of antimalarial drugs artemisinin and artemether in human lymphocytes
  Artemisinin / Leukaemia / (In Vitro)
• Dihydroartemisinin inhibits colon cancer cell viability by inducing apoptosis through up-regulation of PPARγ expression
  Artemisinin / Colon / (In Vitro)
• Dihydroartemisinin increases gemcitabine therapeutic efficacy in ovarian cancer by inducing reactive oxygen species
  Artemisinin / Ovarian / (In Vitro, In Vivo, Chemo, Synergy)
• Artemisinin enhances the anti-tumor immune response in 4T1 breast cancer cells in vitro and in vivo
  Artemisinin / Breast / (In Vitro, In Vivo)
• Transferrin receptor-dependent cytotoxicity of artemisinin–transferrin conjugates on prostate cancer cells and induction of apoptosis
  Artemisinin / Prostate / (In Vitro)
• Synergistic Cytotoxicity of Artemisinin and Sodium Butyrate on Human Cancer Cells
  Artemisinin / Leukaemia / (In Vitro, Synergy)
• Novel multifunctional nanocarrier-mediated codelivery for targeting and treatment of prostate cancer
  Artemisinin / Prostate / (In Vitro, Chemo, Synergy)